Lumefantrine Impurity 2 CAS 355841-11-1(Free base)
| CAS No. | 355841-11-1(Free base) |
| Molecular Formula | C26H24Cl3NO |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 509.29 g/mol gives Lumefantrine Impurity 2 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Lumefantrine Impurity 2 (CAS 355841-11-1(Free base)) is a certified pharmaceutical impurity reference standard with the molecular formula C26H24Cl3NOHCl and a molecular weight of 509.29 g/mol.
Based on its molecular formula C26H24Cl3NOHCl, Lumefantrine Impurity 2 contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 509.29 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Lumefantrine Impurity 2 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C26H24Cl3NO HCl |
| Molecular Weight | 509.29 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Lumefantrine Standards
- Lumefantrine D18 (CAS 1185240-53-2)
- Lumefantrine Impurity 1 (CAS 1331642-68-2)
- (9E)-Lumefantrine (CAS 1456736-33-6)
- Lumefantrine Impurity 4 (CAS 1795128-25-4)
- Lumefantrine Impurity 3 (CAS 1795129-61-1)
- LUMEFANTRINE (CAS 204133-10-8)
- Lumefantrine Impurity 14 (CAS 2170653-95-7)
- Lumefantrine Impurity N1 (CAS 2170653-95-7 (free base))
Recommended Standards
- Axitinib Impurity 65 (CAS CATO-C4X-107165)
- Cephalexin Impurity 42 (CAS 52210-38-5)
- Mianserin impurity 37 (CAS CATO-C4X-136937)
- Tert-butyl 1,4-diazepane-1-carboxylate Hydrochloride (CAS 1049743-87-4)
- 2-Chloro-N-(2-chloro-4-nitrophenyl)propanamide (CAS 379254-98-5)
- 2-(1,3-Dioxaindan-5-yl)-1,3-thiazole-4-carbaldehyde (CAS 885278-54-6)
- 3,5-Dimethyl-4-nitrobenzoic acid (CAS 3095-38-3)
- 1-(1-Methyl-1H-indol-3-yl)-3-(thiazol-2-yl)urea (CAS 899947-32-1)
- Norcarfentanil (CAS 72996-78-2)
- Des-Asp15-Tirzepatide (CAS CATO-CPTD788958)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com